What to expect while on REVTORPYK-based treatment
In the VIKTORIA-1 clinical trial, about 9 out of 10 people were able to continue taking REVTORPYK-based treatment even if side effects occurred
- 88% of people who received REVTORPYK + fulvestrant + palbociclib did not stop treatment due to side effects
- 91% of people who received REVTORPYK + fulvestrant did not stop treatment due to side effects
Like all medicines, side effects may occur during treatment with REVTORPYK. REVTORPYK may cause serious side effects. These include mouth sores (stomatitis), skin reactions, high blood sugar levels (hyperglycemia), and potential harm to an unborn baby if you are pregnant.
The most common side effects of REVTORPYK + fulvestrant + palbociclib include:
- decreased white blood cell counts
- decreased red blood cell counts
- mouth sores
- nausea
- decreased platelet counts
- increased sugar levels (glucose) in the blood
- tiredness
- vomiting
- rash
- constipation
- diarrhea
- increased liver function tests
- muscle and joint pain
- decreased sodium levels in the blood
- increased number of eosinophils (a type of white blood cell) in the blood
The most common side effects of REVTORPYK + fulvestrant include:
- mouth sores
- increased sugar levels (glucose) in the blood
- increased number of eosinophils (a type of white blood cell) in the blood
- decreased red blood cell counts
- nausea
- rash
- increased liver function tests
- tiredness
- muscle and joint pain
- vomiting
- itching
- diarrhea
These are not all the possible side effects of REVTORPYK. See the REVTORPYK Important Facts for more details.
Your oncologist may change your dose, temporarily stop, or permanently stop treatment with REVTORPYK if you have certain side effects. Tell your care team about any new or worsening side effects
What you can do
Mouth sores (stomatitis)
Mouth sores are common with REVTORPYK and may be severe. To help reduce the risk of mouth sores, your oncologist will prescribe an alcohol-free, steroid-containing mouthwash as you begin treatment with REVTORPYK. This mouthwash is used for 2 minutes at a time, 4 times a day, for the first 8 weeks of treatment, or as instructed by your care team.
For 2 minutes
at a time
Use
4x a day
For the first
8 weeks
of
treatment
Tell your care team if you develop any new or worsening changes in your mouth, including:
- pain
- swelling
- redness
- ulcers
Rash
REVTORPYK can cause severe rash. Talk with your oncologist about treatment options to reduce the risk of rash or treat a rash, such as allergy medicines like antihistamines, before starting or with REVTORPYK.
Tell your care team or get medical help right away if you get a new or worsening rash.
Hyperglycemia
High blood sugar can occur with REVTORPYK and may be severe. Your care team will monitor your blood sugar levels before starting and during treatment with REVTORPYK. It is not known if REVTORPYK is safe in people with Type 1 diabetes or Type 2 diabetes that is not controlled.
Tell your care team if you develop any symptoms of high blood sugar, including:
- excessive thirst
- more frequent urination than usual or a higher amount of urine than normal
- blurred vision
- confusion
- headache
- increased appetite with weight loss
- tiredness
Your care team is there to help. Tell them about any changes in your health that bother you or side effects you experience.
