Dosing for REVTORPYK-based treatment

How REVTORPYK is given

How you will receive REVTORPYK-based treatment

REVTORPYK is not chemotherapy—it is a targeted therapy given as an IV infusion, which may reduce the risk of certain side effects.

REVTORPYK is given as an infusion over 30 minutes on days 1, 8, and 15 of a 28-day treatment cycle

Dosage
REVTORPYK
180 mg
Infusion time
GIVEN AS AN INFUSION FOR
30 minutes
Schedule
Administered on
days 1, 8, and 15
  • If you miss a planned visit for REVTORPYK, call your oncologist right away to schedule an appointment
    • Do not wait until the next planned treatment cycle

If you have certain side effects while taking REVTORPYK, your oncologist may change your dose, pause treatment, or stop treatment.

Before taking REVTORPYK

Tell your care team about all your medical conditions, including if you:

  • have diabetes
  • are pregnant or plan to become pregnant. REVTORPYK can harm your unborn baby
  • are breastfeeding or plan to breastfeed. It is not known if REVTORPYK passes into breast milk

Tell your care team about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Keep an up-to-date list of your medicines and share it with your care team or pharmacist when starting a new medicine.

Dosing schedule

What your treatment schedule looks like

Dosing schedule for REVTORPYK + fulvestrant ± palbociclib* (28-day cycle)

REVTORPYK
Palbociclib (if prescribed)
No infusion
Fulvestrant (†Additional dose of fulvestrant is needed on day 15 for the first cycle only.)

*Your treatment may not include palbociclib.

Treatment with fulvestrant ± palbociclib

Fulvestrant is given by your oncologist as an injection into each buttock muscle. You will receive it on days 1 and 15 of the first 28-day cycle. Starting with the second cycle, you will receive fulvestrant on day 1 only.


Palbociclib (if prescribed) is a tablet taken orally once a day for 3 weeks. This is followed by a week with no tablets.

IV=intravenous.